ABSTRACT
Dooshivisha (cumulative toxicity) is a type of Kritrima visha (artificial poison). It is a transformed state of other types of poison if not eliminated, get collected in small doses leads to this type of poisoning. It is a unique concept of Ayurveda and is the cause of the majority of the health issues in the present era. Acharyas have said different treatment principles for the management of Dooshivisha (cumulative toxicity). Dooshivishari agada is the formulation of choice for its treatment, which is a herbo-mineral formulation comprised of twelve ingredients that are taken in equal amounts for the preparation. Many Acharyas such as Sushruta, Vagbhata, and Bhavaprakasha have explained it in their classical texts. Along with Dooshivisha (cumulative toxicity), it can also be used in its complications, and also for the treatment of all types of poisoning and other associated signs and symptoms.
ABSTRACT
Hoarseness of voice is a very common symptom and needs thorough clinical examination and investigation to determine the underlying cause in every patient. The spectrum of the symptom ranges from minor infections to life threating malignancies. Acute onset causes may be due to secondary viral infections, voice abuse, smoking, trauma to the larynx during thyroid surgeries. Chronic onset may be due to vocal polyp, vocal cord nodules, laryngeal papillomatosis, laryngeal neoplasms, tumours of the vocal cord, functional dysphonia, smoking, gastro-oesophageal reflux, malignancy of thyroid, oesophagus, lungs and neurological involvement by systemic disease like diabetes and TB. We wanted to evaluate the common causes of hoarseness of voice.METHODSThis was a longitudinal study conducted among 100 patients with benign laryngeal lesions attending the Department of ENT-HNS of Rajarajeswari Medical College and Hospital, from 1st December 2015 to 31st November 2016. A detailed history including information on patient’s demographics, clinical presentation, history of trauma, along with history of associated medical and surgical condition was obtained. A thorough systemic examination and laryngeal examination was done.RESULTSMale:Female ratio was noted to be 1.7:1. Labourers constituted the single largest group of patients comprising of about 36% of cases. Three fourth of patients were from the rural area. Duration of hoarseness ranged from 1 day (acute onset) to 5 yrs. (mean - 3 months). Septic foci in oral cavity and oropharynx were noted in 42% cases. Apart from change in voice other common symptoms were cough, fever and vocal fatigue. Signs of chronic laryngitis were noted in majority of the cases (22%).CONCLUSIONSThe spectrum of etiological factors for hoarseness varies from minor functional voice disorders to major pathological conditions such as malignancy. Septic foci are important predisposing factor for chronic laryngitis.
ABSTRACT
Background: Abnormal uterine bleeding (AUB) is the most common complaint in gynecology and an important source ofmorbidity. It may be evaluated by hysteroscopy or by dilatation and curettage.Materials and Methods: Between January 2015 and August 2016, 50 patients with AUB who got admitted at MNR MedicalCollege in the Department of Obstetrics and Gynaecology were subjected to panoramic hysteroscopy and subsequent dilatationand curettage. Data were collected and analyzed.Results: AUB was more common in 30–39 years. The most common presenting complaint was menorrhagia. Negativehysteroscopic view was seen in 54% of cases. Abnormalities seen were endometrial hyperplasia, polyps, submucous myoma, andendometrial atrophy. Both hysteroscopy and curettage were accurate when an abnormality was diagnosed, giving a specificity of96.15% and positive predictive value of 96.65%. However, the ability to diagnose a lesion (sensitivity) was more with hysteroscopyin comparison to curettage (91.66 vs. 79.16). Forty-one patients (82%) had the same tissue diagnosis in both hysteroscopy andcurettage. Hysteroscopy revealed more information than curettage in 12% and curettage had more information in 6% of cases.Conclusion: This study confirms the conclusion of many others that hysteroscopy is superior to dilatation and curettage inevaluating patients with AUB.
ABSTRACT
Background: Cardiovascular diseases (CVD) are the leading cause of death throughout world population each and every year. Focus on dyslipidemia management is urgently required in India to halt the rising tide of CVD. The purpose of diabetic dyslipidemia study is a record based one, to find out the effect of Rosuvastatin plus Fenofibrate, in adult Type 2 diabetes with dyslipidemia, with high TGL/HDL ratio in Lipid profiles, in a tertiary care hospital in the Union territory of Puducherry.Methods: There were 101 patients hospital records were analysed in which male were 45 and females were 56. The various biochemical parameters like serum Total Cholesterol, HDL, LDL, TGL, Non-HDL, TCL/HDL Ratio and TGL/HDL ratio reports were collected before and after 12-weeks of Rosuvastatin 10 mg with Fenofibrate 145 mg combination, for the treatment period once daily for their lipid-lowering therapy.Results: The combination therapies of Rosuvastatin plus Fenofibrate were safe and feasible to achieve more TG goal and proved that has predominately decreased the elevated lipid profiles from the medical resources of our record based study. The use of combination medications of rosuvastatin (10mg) plus Fenofibrate (145mg) is often needed to effectively treat the lipid triad, by the potency of rosuvastatin to lower LDL-C and Fenofibrates effectiveness in lowering TG in treating mixed diabetic dyslipidemia.Conclusions: After Rosuvastatin (10mg) plus Fenofibrate (145mg), the lipid profile data proved that the importance of TGL/HDL ratio apart from the TCL/HDL ratio, for good lipid control in diabetic dyslipidemic patients.